為HyClone所推出之CHO細胞專用血清，經過100 nm濾膜進行3次過濾，基本成分與FetalClone I相同，且有額外添加生長因子及其他營養物質。經測試除了CHO亦能成功培養下列細胞：

FetalClone II
Cell Line	Description	Cell Line	Description
JEG3	Human choriocarcinoma	BHK	Body hamster kidney fibroblast
L929	Murine areolar and adipose fibrosarcoma	NIH/3T3	Murine embryonic fibroblast
C3H/10T1/2	Murine embryonic fibroblast	U-937	Human histiocytic lymphoma
PC-12	Murine adrenal gland pheochromocytoma	U9-IIIB	Human histiocytic lymphoma
Pancreatic cells	Murine	P3X63 Ag8.653	Murine myeloma/ hydridoma
L(-tk)	Murine L cell connective tissue	NS1	Murine myeloma/ hydridoma
SH-SYSY	Human neuroblastoma	P3	Murine myeloma/ hydridoma
HEK-293	Human embryonic kidney	HeLa	Human epithelial adenosarcoma
Hep 3B2	Human liver epithelial carcinoma	HEp-2	Human epithelial adenocarcinoma
9HTEo	Human epithelial trachea	MDBK	Bovine kidney
Sp2/0-Ag14	Murine myeloma/ hydridoma	Jurkat T-lymphocyte	Human thymoma
FOX-NY	Murine myeloma/ hydridoma	COS	Africa green monkey kidney fibroblast

產地: 美國。